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The FDA reports, “There is a possible increased risk of fractures of the hip, wrist, and spine if you take certain drugs for heartburn, acid reflux, or ulcers.”

The drugs belong to a class of medications called proton pump inhibitors (PPIs), which work by reducing the amount of acid in the stomach. They are available both as prescription and as over-the-counter (OTC) medications. The prescription PPIs treat conditions such as gastroesophageal reflux disease (GERD), ulcers in the stomach and small intestine, and inflammation of the esophagus. 

The prescription PPIs are

  • Nexium
  • Dexilant
  • Prilosec
  • Zegerid
  • Prevacid
  • Protonix
  • Aciphex
  • Vimovo

The over-the-counter PPIs are

  • Prilosec OTC (omeprazole)
  • Zegerid OTC (omeprazole)
  • Prevacid 24HR (lansoprazole)

Advice for Consumers

The FDA does not recommend the use of these drugs for more than 14 days. For resistan